Dynamic constrained coalition formation among electric vehicles

Background: The use of electric vehicles (EVs) and vehicle-to-grid (V2G) technologies have been advocated as an efficient way to reduce the intermittency of renewable energy sources in smart grids. However, operating on V2G sessions in a cost-effective way is not a trivial task for EVs. The formation of coalitions among EVs has been proposed to tackle this problem. Methods: In this paper we introduce Dynamic Constrained Coalition Formation (DCCF), which is a distributed heuristic-based method for constrained coalition structure generation (CSG) in dynamic environments. In our approach, coalitions are formed observing constraints imposed by the grid. To this end, EV agents negotiate the formation of feasible coalitions among themselves. Results: Based on experiments, we show that DCCF is efficient to provide good solutions in a fast way. DCCF provides solutions whose quality approaches 98% of the optimum. In dynamically changing scenarios, DCCF also shows good results, keeping the agents payoff stable along time. Conclusions: Essentially, DCCF’s main advantage over traditional CSG algorithms is that its computational effort is very lower. On the other hand, unlike traditional algorithms, DCCF is suitable only for constraint-based problems

Fostering cooperation through dynamic coalition formation and partner switching

In this article we tackle the problem of maximizing cooperation among self-interested agents in a resource exchange environment. Our main concern is the design of mechanisms for maximizing cooperation among self-interested agents in a way that their profits increase by exchanging or trading with resources. Although dynamic coalition formation and partner switching (rewiring) have been shown to promote the emergence and maintenance of cooperation for self-interested agents, no prior work in the literature has investigated whether merging both mechanisms exhibits positive synergies that lead to increase cooperation even further. Therefore, we introduce and analyze a novel dynamic coalition formation mechanism, that uses partner switching, to help self-interested agents to increase their profits in a resource exchange environment. Our experiments show the effectiveness of our mechanism at increasing the agents' profits, as well as the emergence of trading as the preferred behavior over different types of complex networks. © 2014 ACM.The first author thanks the grant Formación de Profesorado Universitario (FPU), reference AP2010-1742. J.Ll.A. and J.A.R-A are partially funded by projects EVE (TIN2009-14702-C02-01), AT (CSD2007-0022), COR (TIN2012-38876-C02-01), MECER (201250E053), and the Generalitat of Catalunya grant 2009-SGR-1434Peer Reviewe

Using reputation and adaptive coalitions to support collaboration in competitive environments

Internet-based scenarios, like co-working, e-freelancing, or crowdsourcing, usually need supporting collaboration among several actors that compete to service tasks. Moreover, the distribution of service requests, i.e., the arrival rate, varies over time, as well as the service workload required by each customer. In these scenarios, coalitions can be used to help agents to manage tasks they cannot tackle individually. In this paper we present a model to build and adapt coalitions with the goal of improving the quality and the quantity of tasks completed. The key contribution is a decision making mechanism that uses reputation and adaptation to allow agents in a competitive environment to autonomously enact and sustain coalitions, not only its composition, but also its number, i.e., how many coalitions are necessary. We provide empirical evidence showing that when agents employ our mechanism it is possible for them to maintain high levels of customer satisfaction. First, we show that coalitions keep a high percentage of tasks serviced on time despite a high percentage of unreliable workers. Second, coalitions and agents demonstrate that they successfully adapt to a varying distribution of customers' incoming tasks. This occurs because our decision making mechanism facilitates coalitions to disband when they become non-competitive, and individual agents detect opportunities to start new coalitions in scenarios with high task demand. © 2015 Elsevier Ltd. All rights reserved.The first author thanks the grant Formación de Profesorado Universitario (FPU), reference AP2010-1742. Arcos and Rodriguez-Aguilar thank projects COR (TIN2012-38876-C02-01/02) and Generalitat of Catalunya (2014 SGR-118). Work supported by the European Regional Development Fund (ERDF) and the Galician Regional Government under agreement for funding the Atlantic Research Center for Information and Communication Technologies (AtlantTIC)Peer Reviewe

USING TAGS IN AN AIML-BASED CHATTERBOT TO IMPROVE ITS KNOWLEDGE

Nowadays, it is common to find on the Internet different conversational robots which interact with users simulating a natural language conversation. Among them, we can emphasize the chatterbots based on AIML language. In this paper we present an AIML based chatterbot that shows as its main contribution the use of tags and folksonomies. Thanks to its use, we can generate a context for each conversation, being able to maintain a state for each user in the system, and improving the adaptation capabilities of the bot

Emerging Cooperation in N-Person Iterated Prisoner's Dilemma over Dynamic Complex Networks

The N-Person Iterated Prisoner's Dilemma (NIPD) is an interesting game that has proved to be very useful to explore the emergence of cooperation in multi-player scenarios. Within this game, the way that agents are interconnected is a key element that influences cooperation. In this context, complex networks provide a realistic model of the topological features found in Nature and in many social and technological networks. Considering these networks, it is interesting to study the network evolution, given the possibility that agents can change their neighbors (dynamic rewire), when non-cooperative behaviors are detected. In this paper, we present a model of the NIPD game where a population of genetically-coded agents compete altogether. We analyze how different game parameters, and the network topology, affect the emergence of cooperation in static complex networks. Based on that, we present the main contribution of the paper that concerns the influence of dynamic rewiring in the emergence of cooperation over the NIPD

Non-conventional yeasts as hosts for heterologous protein production.

Yeasts are an attractive group of lower eukaryotic microorganisms, some of which are used in several industrial processes that include brewing, baking and the production of a variety of biochemical compounds. More recently, yeasts have been developed as host organisms for the production of foreign (heterologous) proteins. Saccharomyces cerevisiae has usually been the yeast of choice, but an increasing number of alternative non-Saccharomyces yeasts has now become accessible for modern molecular genetics techniques. Some of them exhibit certain favourable traits such as high-level secretion or very strong and tightly regulated promoters, offering significant advantages over traditional bakers' yeast. In the present work, the current status of Kluyveromyces lactis, Yarrowia lipolytica, Hansenula polymorpha and Pichia pastoris (the best-known alternative yeast systems) is reviewed. The advantages and limitations of these systems are discussed in relation to S. cerevisiae.Spanish Society for Microbiolog

Non-conventional yeasts as hosts for heterologous protein production

Yeasts are an attractive group of lower eukaryotic microorganisms, some of which are used in several industrial processes that include brewing, baking and the production of a variety of biochemical compounds. More recently, yeasts have been developed as host organisms for the production of foreign (heterologous) proteins. Saccharomyces cerevisiae has usually been the yeast of choice, but an increasing number of alternative non-Saccharomyces yeasts has now become accessible for modern molecular genetics techniques. Some of them exhibit certain favourable traits such as high-level secretion or very strong and tightly regulated promoters, offering significant advantages over traditional bakers’ yeast. In the present work, the current status of Kluyveromyces lactis, Yarrowia lipolytica, Hansenula polymorpha and Pichia pastoris (the best-known alternative yeast systems) is reviewed. The advantages and limitations of these systems are discussed in relation to S. cerevisiae

Estrategias de mejora en la evaluación del TFM del Máster en Evaluación y Desarrollo de Medicamentos

Memoria ID-0041. Ayudas de la Universidad de Salamanca para la innovación docente, curso 2016-2017

Seroprevalence of SARS-CoV-2 Antibodies and Factors Associated with Seropositivity at the University of Salamanca: The DIANCUSAL Study

© 2021 by the authors[Background]: Systematic screening for antibodies against SARS-CoV-2 is a crucial tool for surveillance of the COVID-19 pandemic. The University of Salamanca (USAL) in Spain designed a project called “DIANCUSAL” (Diagnosis of New Coronavirus, COVID-19, in University of Salamanca) to measure antibodies against SARS-CoV-2 among its ~34,000 students and academic staff, as the influence of the university community in the spread of the SARS-CoV-2 pandemic in the city of Salamanca and neighboring towns hosting USAL campuses could be substantial.[Objective]: The aim of this study was to estimate the prevalence of SARS-CoV-2 antibodies among USAL students, professors and staff and to evaluate the demographic, academic, clinical and lifestyle and behavioral factors related to seropositivity.[Methodology]: The DIANCUSAL study is an ongoing university population-based cross-sectional study, with the work described herein conducted from July–October 2020. All USAL students, professors and staff were invited to complete an anonymized questionnaire. Seroprevalence of anti-SARS-CoV-2 antibodies was detected and quantified by using chemiluminescent assays for IgG and IgM. Principal findings: A total of 8197 (24.71%) participants were included. The mean age was 31.4 (14.5 SD) years, and 66.0% of the participants were female. The seroprevalence was 8.25% overall and was highest for students from the education campus (12.5%) and professors from the biomedical campus (12.6%), with significant differences among faculties (p = 0.006). Based on the questionnaire, loss of smell and fever were the symptoms most strongly associated with seropositivity, and 22.6% of seropositive participants were asymptomatic. Social distancing was the most effective hygiene measure (p = 0.0007). There were significant differences in seroprevalence between participants with and without household exposure to SARS-CoV-2 (p = 0.0000), but not between students who lived in private homes and those who lived in dormitories. IgG antibodies decreased over time in the participants with confirmed self-reported COVID-19 diagnoses.[Conclusions]: The analysis revealed an overall 8.25% seroprevalence at the end of October 2020, with a higher seroprevalence in students than in staff. Thus, there is no need for tailored measures for the USAL community as the official average seroprevalence in the area was similar (7.8% at 22 June and 12.4 at 15 November of 2020). Instead, USAL members should comply with public health measures.The DIANCUSAL (Diagnosis of New Coronavirus, COVID-19, in University of Salamanca) study was funded by a grant from the University of Salamanca (USAL)

Validation of the spanish version of the multiple sclerosis international quality of life (musiqol) questionnaire

<p>Abstract</p> <p>Background</p> <p>The Multiple Sclerosis International Quality Of Life (MusiQoL) questionnaire, a 31-item, multidimensional, self-administrated questionnaire that is available in 14 languages including Spanish, has been validated using a large international sample. We investigated the validity and reliability of the Spanish version of MusiQoL in Spain.</p> <p>Methods</p> <p>Consecutive patients with different types and severities of multiple sclerosis (MS) were recruited from 22 centres across Spain. All patients completed the MusiQoL questionnaire, the 36-Item Short Form (SF-36) health survey, and a symptoms checklist at baseline and 21 days later. External validity, internal consistency, reliability and reproducibility were tested.</p> <p>Results</p> <p>A total of 224 Spanish patients were evaluated. Dimensions of MusiQoL generally demonstrated a high internal consistency (Cronbach's alpha: 0.70-0.92 for all but two MusiQoL domain scores). External validity testing revealed that the MusiQoL index score correlated significantly with all SF-36 dimension scores (Pearson's correlation: 0.46-0.76), reproducibility was satisfactory (intraclass correlation coefficient: 0.60-0.91), acceptability was high, and the time taken to complete the 31-item questionnaire was reasonable (mean [standard deviation]: 9.8 [11.8] minutes).</p> <p>Conclusions</p> <p>The Spanish version of the MusiQoL questionnaire appears to be a valid and reliable instrument for measuring quality of life in patients with MS in Spain and constitutes a useful instrument to measure health-related quality of life in the clinical setting.</p